Dwayne Roloson came up big early, making a pair of big saves as Tampa Bay pressured early. He denied Prospal on the initial shot form the slot and then gloved the rebound out of mid-air.
The OIlers' line of Cogliano, Gagner and Nilsson made their presence known early in the game. Speed and strong forechecking resulted in forcing Lightning defenceman Doug Janik to take a penalty for interference.
Edmonton's defenders were able to curb the Lightning offence through most of the period. Tampa Bay didn't have a shot on goal during a two-minute power play past the midway point of the first and in fact did not manage a shot in the latter half of the opening period.
Shots on goal after one period were 6-3 for Edmonton.
38 seconds into the second period, Tampa Bay scored to take the lead. Jan Hlavac had Roloson at his mercy but couldn't find an opening to shoot the puck past the Oilers netminder.
Instead, he fed the puck back to Martin St. Louis in the high slot who spotted Brad Richards to the right side of the net. Roloson couldn't get across in time as Richards put the puck into the open cage.
On the next shift, Fernando Pisani was denied at the top of the crease by Holmqvist. He tried to get the puck around the Lightning netminder but Holmqvist stretched to get his glove on the puck.
4:29 into the period, Craig MacDonald intercepted Tom Gilbert's outlet pass then blasted a shot from the left circle past Roloson to increase the Lightning lead to 2-0.
Roloson came up with a big save several minutes later on a redirection attempt after Hlavac took a pass from St. Louis.
Edmonton went on the power play near the midway point of the period but it was Tampa Bay that capitalized with a shorthanded marker to take a 3-0 lead.
Martin St. Louis carried the puck down the ice and slipped it five-hole past Roloson for the goal.
On that same power play, Andrew Cogliano got one back for the Oilers. Cogliano fired a shot over the left pad of Holmqvist to close the gap to 3-1. Gagner and Pitkanen got the assists.
Prospal almost made it a three-goal game once again when his shot from the left circle hit Roloson's pad then dribbled across the goalmouth.
Shots on goal after two were 16-14 for the Lightning.
Tampa Bay scored on a power play about five minutes into the third period. The Oilers were caught on a line change and St. Louis threaded the puck up ice to send Lecavalier in on a partial break. His shot beat Roloson five hole to increase the Lightning lead to 4-1.
Near the end of a productive shift from Cogliano, Nilsson and Gagner the Oilers struck to make it a two-goal game once again. Cogliano threw the puck back to Steve Staios in the high slot and his blast beat Holmqvist low for the goal.
With 3:24 left in the third, Penner's shot from the left circle almost fooled the Lightning goaltender. He lost sight of the puck momentarily as it slipped under his pads but ultimately had it covered.
With just over a minute to play in the third, Ales Hemsky wristed the puck over the shoulder of Holmqvist to close the gap to 4-3 but that was as close as the Oilers would get.
NOTES: Johan Holmqvist's shutout streak ended at 151:37 after Cogliano's goal.